Catherine Stein

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  Genetic Studies of Tuberculosis: Importance of the Family-based Design
  Catherine Stein

  Tuberculosis (TB) remains a major public health threat globally, and several studies have demonstrated a role for human genetic factors underlying TB risk. However, exposure to the causal bacterium, Mycobacterium tuberculosis, is a necessary risk factor for TB, and few population-based studies appropriately account for this exposure. In this talk, I will describe how we’ve utilized a family study to examine the genetic epidemiology of TB and address limitations in the extant literature. I will present both key findings and future directions.

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  Novel human genetic approaches to studying tuberculosis resistance
  Catherine Stein